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ea0086p208 | Metabolism, Obesity and Diabetes | SFEBES2022

Serum Bile Acid Measurements in Women of European and South Asian Descent with or without Gestational Diabetes Mellitus

Schoonejans Josca , Man Fan Hei , Mitchell Alice , Lovgren-Sandblom Anita , Syngelaki Argyro , Sukumar Nithya , Periyathambi Nishanti , Nicolaides Kypros , Seed Paul , Molinaro Antonio , Marschall Hanns-Ulrich , Saravanan Ponnusamy , Williamson Catherine

Introduction: Bile acid (BA)-feeding and genetic manipulation of BA receptors affect glucose tolerance in rodent pregnancy. In non-pregnant individuals, serum BA profiles depend on BMI and ethnicity. The interaction between serum BAs, ethnicity, and BMI in gestational diabetes mellitus (GDM) remains poorly understood.Methods: Fasted serum samples were collected between 23-31 weeks gestation. Experimental groups: lean or obese women of European (EU)...

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Serum Bile Acid Measurements in Women of European and South Asian Descent with or without Gestational Diabetes Mellitus

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